Molecular characterization of human rhinovirus strains detected in pediatric acute respiratory tract infections

Iranian Journal of Microbiology 2026 Open access

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Authors: V R Parvathy, Pryanka Thakur, Vikram Thakur, Vikrant Sharma, Ishani Bora, Radha Kanta Ratho, Suresh Kumar Angurana, Mini P. Singh
DOI: 10.18502/ijm.v18i1.21031
Cited by: 0

Abstract

Background and Objectives: Acute respiratory tract infections (ARTI) are a leading cause of morbidity and mortality in children worldwide, accounting for approximately 18% of deaths in those 1 month to 1 year, HRV positivity was significantly associated with severe acute respiratory infection (SARI) compared with influenza-like illness (ILI). Phylogenetic analysis revealed a predominance of HRV-C strains (n = 7), followed by HRV-A (n = 5) and HRV-B (n = 1). Conclusion: HRV was detected in a significant proportion of pediatric ARTI cases, with HRV-C as the predominant strain. Infants aged >1 month to 1 year showed a higher association with severe illness, underscoring the need for closer clinical monitoring in this age group.

Fields of Study & Subjects

Respiratory viral infections research Viral Infections and Immunology Research Viral gastroenteritis research and epidemiology

Publication details

Journal / source
Iranian Journal of Microbiology
Volume
18
Issue
1
Pages
122–130
Publication date
15 February 2026
Language
EN