BENIGN FIBROUS HISTIOCYTOMA (DERMATOFIBROMA): A CASE REPORT

Background: Benign fibrous histiocytoma (BFH), also known as dermatofibroma, is a common benign cutaneous mesenchymal tumor. Despite its benign nature, it may mimic other spindle cell lesions clinically and histologically, necessitating accurate diagnostic evaluation. Case Presentation: We report a case of a patient presenting with a slowly growing, painless cutaneous dermal nodule. Complete local surgical excision was performed for diagnostic and therapeutic purposes. Histopathological Findings: Microscopic examination revealed a dermal-based spindle cell proliferation arranged in a storiform pattern, composed of fibroblast-like cells without cytologic atypia, necrosis, or increased mitotic activity. Immunohistochemical analysis showed positivity for CD68 and negativity for CD34, supporting the diagnosis of benign fibrous histiocytoma and excluding malignant spindle cell neoplasms. Conclusion: This case highlights the importance of histopathological evaluation supported by immunohistochemical analysis in the accurate diagnosis of benign fibrous histiocytoma. In the present case, complete surgical excision was followed by a favorable outcome, reinforcing the value of a systematic diagnostic approach.