Decide less, communicate more: On the construct validity of end-to-end fact-checking in medicine

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Authors: Sebastian Joseph, Lily Chen, Barry Wei, Michael Mackert, Iain James Marshall, Paul Pu Liang, Ramez Kouzy, Byron Wallace, Junyi Jessy Li
Cited by: 0

Abstract

Technological progress has led to concrete advancements in tasks that were regarded as challenging, such as automatic fact-checking. Interest in adopting these systems for public health and medicine has grown due to the high-stakes nature of medical decisions and challenges in critically appraising a vast and diverse medical literature. Evidence-based medicine connects to every individual, and yet the nature of it is highly technical, rendering the medical literacy of majority users inadequate to sufficiently navigate the domain. Such problems with medical communication ripen the ground for end-to-end fact-checking agents: check a claim against current medical literature and return with an evidence-backed verdict. And yet, such systems remain largely unused. In this position paper, developed with expert input, we present the first study examining how clinical experts verify real claims from social media by synthesizing medical evidence. In searching for this upper-bound, we reveal fundamental challenges in end-to-end fact-checking when applied to medicine: Difficulties connecting claims in the wild to scientific evidence in the form of clinical trials; ambiguities in underspecified claims mixed with mismatched intentions; and inherently subjective veracity labels. We argue that fact-checking should be approached as an interactive communication problem, rather than an end-to-end process. Data and code are available at https://github.com/SebaJoe/decide-less-communicate-more.

Fields of Study & Subjects

Misinformation and Its Impacts Topic Modeling Artificial Intelligence in Healthcare and Education

Publication details

Journal / source
Findings of the Association for Computational Linguistics: ACL 2026
Publisher
Association for Computational Linguistics
Volume
2026
Pages
10196–10221
Publication date
1 January 2026
Language
EN