Analysis of prognostic factors in metastatic colon cancer

Aim: Colorectal cancer (CRC) ranks as the second leading cause of cancer-related deaths and the third most common cancer globally. However, due to the complexity of tumor biology, identifying reliable prognostic factors remains crucial. Material and Methods: We conducted a retrospective analysis of 71 patients with metastatic colon cancer who were followed at Balikesir Ataturk City Hospital. The platelet-to-lymphocyte ratio (PLR), neutrophil-to-lymphocyte ratio (NLR), and systemic immune-inflammation index (SII) were calculated. Survival analysis was performed using the Kaplan-Meier method and prognostic factors were evaluated with Cox regression analysis. Results: The median overall survival (OS) was 34.8 months. Survival was significantly shorter in patients with a BMI