Predictors of six-month mortality after emergency haemodialysis for acute kidney injury in adults living with HIV: a retrospective cohort study

Abstract Background: Acute kidney injury (AKI) occurring in people living with HIV (PLWH) remains a significant clinical challenge in low- and middle-income countries (LMICs). This study aimed to evaluate the utility of immunovirological status, comorbidity burden, and dialysis indications in predicting six-month outcomes in PLWH undergoing emergency haemodialysis. Methods: A retrospective study of 150 patients with PLWH who received emergency dialysis for AKI between 2018 and 2023. Predictors of six-month mortality were assessed using multivariable logistic regression. Frailty was measured via the Clinical Frailty Scale (CFS), and the AEIOU (Acidosis, Electrolyte imbalances, Intoxications, fluid Overload, and Uraemia) criteria were applied to dialysis triggers. Results: The study cohort had a mean age of 46.3±13.8 years, 57.3% were male, 40.7% were hypertensive, and 28% had diabetes. CD4 count and HIV viral load were strong predictors of six-month mortality (p