カガクリョウホウ ユウハツセイ マッショウシンケイ ショウガイ ヲ モツ ガン カンジャ ノ セイカツ サイコウチク ニ ムケタ チシキ キョウユウ システム ジツヨウカ ノ タメ ノ ケントウ ダイ2ホウ システム シヨウ ゼンゴ ノ ヘンカ

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Authors: 瀬奈 山本, セナ ヤマモト, Sena Yamamoto, 美紀 山岸, ミキ ヤマギシ, Yamagishi, Miki, 美和 青木, ミワ アオキ, Miwa Aoki, 惠子 田墨, ケイコ タズミ, Keiko Tazumi
+9 more 徳信 來村, ヨシノブ キタムラ, Yoshinobu Kitamura, 理一郎 溝口, リイチロウ ミゾグチ, Riichiro Mizoguchi, 晴惠 荒尾, ハルエ アラオ, Harue Arao
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Abstract

Objective : We developed an online knowledge-sharing system for life reconstruction of cancer survivors with chemotherapy-induced peripheral neuropathy (CIPN). This study aimed to explore the changes in CIPN and quality of life (QOL) before and after the use of our system toward its implementation. Methods : A self-administered questionnaire survey was used. Ten patients with cancer and CIPN undergoing outpatient chemotherapy used the system for approximately 15–20 min. The severity of CIPN symptoms, impact of CIPN, and QOL were evaluated using the Functional Assessment of Cancer Therapy/Gynecologic Oncology Group – Neurotoxicity, Comprehensive Assessment Scale for Chemotherapy-induced Peripheral Neuropathy in Survivors of Cancer, and SF-8, respectively. The measures were assessed at the time of system use and the subsequent treatment cycle. Results: Seven participants were aged 60 years or older. The male-to-female ratio was balanced. CIPN was caused by Oxaliplatin and/or Taxane. No significant differences were found in overall measures before and after using the system. However, on an individual level, participants who remembered the information provided and applied the recommended coping strategies reported improvements in the impact of CIPN and their QOL after using the system. Conclusion : The system may help reduce the impact of CIPN and support the maintenance of QOL by promoting effective use of the information it provides.

Fields of Study & Subjects

Cancer Treatment and Pharmacology Cancer survivorship and care Cancer-related cognitive impairment studies

Publication details

Journal / source
OUKA (Osaka University Knowledge Archive) (Osaka University)
Volume
32
Issue
1
Pages
1–9
Publication date
31 March 2026
Language
JA