Global stability of a class of fractional partial differential equations describing the dynamics of viral infection with therapy and adaptive immunity

Read full text
Authors: Mohammad Eloualy, Abdelaziz El Hassani, Khalid Hattaf, Abdelhafid Bassou
Cited by: 1

Abstract

In this article, we formulate a mathematical model based on fractional partial differential equations (FPDEs) to describe the spatiotemporal progression of viral infections, incorporating the effects of adaptive immunity and antiviral treatment. The model includes a regional fractional Laplace operator to account for the anomalous diffusion observed within the infected medium. We investigate the existence and uniqueness of equilibria and establish their global stability using Lyapunov functions tailored to the associated reaction systems. Moreover, numerical simulations are presented to illustrate the analytical results.

Fields of Study & Subjects

Fractional Differential Equations Solutions Mathematical and Theoretical Epidemiology and Ecology Models Mathematical Biology Tumor Growth

Publication details

Journal / source
Statistics Optimization & Information Computing
Publisher
International Academic Press
Volume
15
Issue
4
Pages
2948–2970
Publication date
8 January 2026
Language
EN