Clinical Features, Diagnosis, and Treatment Approaches in Granulomatous Mastitis: A Single-Center Alternative Treatment Experience

Granulomatous mastitis (GM) is a rare, benign, but chronically progressive inflammatory breast disease. This study evaluated the effect of negative pressure vacuum therapy (NPVT) on postoperative seroma formation in GM. Twelve patients treated between May 2018 and July 2023 were retrospectively analyzed. Patients were divided into two groups: Group 1 underwent abscess drainage and biopsy followed by 48 hours of NPVT before segmental mastectomy, whereas Group 2 underwent drainage and mastectomy in the same session. Seroma formation was assessed by ultrasonography at 3 months. No significant differences were found between groups regarding age, comorbidities, or baseline demographics (p>0.05). Mean seroma size was 1.27 cm in Group 1 and 3.28 cm in Group 2, showing a statistically significant difference (p