DNA Mismatch Repair Protein Expression Status Is Associated with Social Demographic Factors in Endometrial Carcinoma

Objective: The relationship between social demographic factors and biomarker expression is less studied. Methods: We have reviewed 645 endometrial carcinomas with demographic information including race/ethnicity, marital status, religious belief, body mass index (BMI), and pathology staging as well as DNA mismatch repair enzyme expression (MMR) status. Statistical analysis was performed by using various programs in R-package. Results: A total of 645 hysterectomy specimens of endometrial carcinoma, including 463 low grade carcinomas (72%) and 182 high grade carcinomas (28%) were reviewed. Race/ethnicity and marital status were found significantly associated with patient’s age (p