Real-World Useability and Acceptability of the CUE1 Device in Older People with Parkinsonʹs

Objective: To evaluate the feasibility, usability, and preliminary efficacy of the CUE1 wearable vibrotactile device in real-world, clinic-based older adults with Parkinson’s disease (PD). Methods: A single-arm feasibility study was conducted in 20 over 60-year-old participants with PD attending a routine movement disorders clinic. Par-ticipants used the CUE1 device daily for four weeks. Usability and acceptability were assessed through participant diaries. Motor outcomes were evaluated at two timepoint, baseline and after 4 weeks using MDS-UPDRS III and Timed Up and Go (TUG). Results: Sixteen participants completed the study. The CUE1 was well tolerated with minimal adverse events. Statistically significant improvements were observed in MDS-UPDRS III scores (mean change −4.5, p = 0.04) and TUG times (mean change −2.1s, p = 0.009). Im-provements were most pronounced in participants with greater baseline motor im-pairment. Conclusions: The CUE1 device demonstrated good feasibility, high usability, and promising motor improvements in older, real-world patients with PD who are often underrepresented in clinical trials. These findings support further evaluation of the CUE1 in larger, randomized controlled studies to confirm its clinical benefits and real-world applicability.