Oxidative Stress and Skin Aging: Non-Invasive, Real-Time Assessment Using PAOT Technology

Oxidative stress accelerates skin aging by causing damage to DNA, lipids and proteins in skin cells. Exacerbated by environmental factors such as UV rays, pollution and smoking, it leads to loss of elasticity, the appearance of wrinkles, cutaneous dryness, pigmentation spots and a general weakening of the skin's natural defenses. These changes, accumulated over time, are responsible for premature or accelerated aging. Against this backdrop, PAOTScan is an innovative, non-invasive technology for assessing the oxidative state of the skin in real time. The device is based on a patch equipped with microelectrodes and an electrochemical gel. It provides two essential scores: the PAOTScore, which measures the skin's Total Antioxidant Power to neutralize free radicals, and the POTScore (Total Oxidant Power), which quantifies the level of oxidants. These data provide a detailed analysis of the skin's redox balance, enabling early detection of imbalances responsible for premature aging. The PAOTScan not only measures the speed of skin ageing, but also enables prevention and treatment strategies to be adapted. It is therefore an invaluable tool in dermatology and dermato-cosmetics, making it easier to monitor the effectiveness of anti-aging interventions and helping to preserve the skin's health and youthfulness.