The results of recent randomized controlled trials presented at the congress of the European Society of Cardiology: is everything so simple in evaluating their results?
Abstract
The results of randomized controlled trials (RCTs) presented at the recent ESC Congress are being analyzed. A number of RCTs with similar objectives have yielded formally opposite results. This primarily concerns the effectiveness of beta-blockers in modern conditions after a myocardial infarction, as well as the possibility of replacing dual antiplatelet therapy with monotherapy with prasugrel or ticagrelor after a myocardial infarction. However, a thorough analysis of the methodological features of these RCTs reveals that the discrepancies between them are not significant. It is anticipated that the results of several RCTs may be challenging to integrate into the CR.
Fields of Study & Subjects
Antiplatelet Therapy and Cardiovascular Diseases
Acute Myocardial Infarction Research
Statistical Methods in Clinical Trials
Publication details
- Journal / source
- Rational Pharmacotherapy in Cardiology
- Volume
- 21
- Issue
- 5
- Pages
- 492–497
- Publication date
- 14 January 2026
- Language
- RU