TILOOP mesh in immediate prepectoral breast reconstruction via single-port endoscopic axillary approach: a study in early- and mid-stage breast cancer patients

Background: Prepectoral implant-based breast reconstruction (BR) via single-port endoscopic axillary approach reduces visible scarring and incision-related complications. TILOOP mesh may improve implant support and aesthetics, but its added value remains uncertain. This study evaluated outcomes, complications, and patient satisfaction with mesh use. Methods: A retrospective cohort of 383 patients (165 mesh vs. 218 no-mesh) undergoing immediate prepectoral BR via single-port endoscopy [2020–2022] was analyzed. Outcomes included surgical parameters, complications at 30 days/12 months, oncological results at 36 months, and Breast Reconstruction Evaluation and Satisfaction Questionnaire (BREAST-Q) satisfaction. Results: Baseline features were balanced. The mesh group showed slightly lower mean postoperative pain scores and higher breast satisfaction scores; however, these differences did not reach statistical significance (P>0.05). Mesh use was associated with greater blood loss (98.1±62.2 vs. 91.2±42.2 mL, P