Dose-response relationship between ascites volume and survival in high-grade serous ovarian cancer: a prospective cohort study

Gland Surgery 2026 Open access

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Authors: Zhuo Chen, H. Ouyang, Botao Sun, Yalin Zhang, Xinying Li
DOI: 10.21037/gs-2025-aw-481
Cited by: 0

Abstract

Background: Whether ascites volume independently predicts survival in ovarian cancer remains unresolved due to conflicting evidence, binary classification approaches, and the absence of dose-response analysis. This prospective study aimed to characterize the dose-response relationship between ascites volume and survival outcomes and identify clinically meaningful volume thresholds. Methods: We analyzed data from 293 high-grade serous ovarian cancer patients from Xiangya Hospital, Central South University [2017-2020]. Patients were stratified by intraoperative ascites volume: no ascites (0 mL), low-volume (

Fields of Study & Subjects

Ovarian cancer diagnosis and treatment Intraperitoneal and Appendiceal Malignancies Endometrial and Cervical Cancer Treatments

Publication details

Journal / source
Gland Surgery
Volume
15
Issue
2
Pages
39–39
Publication date
1 February 2026
Language
EN