Immune-mediated tumor regression and subsequent escape driven by antigen loss and major histocompatibility complex (MHC) class I downregulation following GPC3 DNA vaccination in hepatocellular carcinoma

HepatoBiliary Surgery and Nutrition 2026 Open access

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Authors: Hang Li, Xudong Wang, Zhentao Yan, Siyuan Weng, Wendi Kang, Junqing Xi, Zhengqiang Yang
DOI: 10.21037/hbsn-2025-aw-806
Cited by: 0

Abstract

Immune-mediated tumor regression and subsequent escape driven by antigen loss and major histocompatibility complex (MHC) class I downregulation following GPC3 DNA vaccination in hepatocellular carcinoma

Fields of Study & Subjects

Immunotherapy and Immune Responses Hepatocellular Carcinoma Treatment and Prognosis Cancer Immunotherapy and Biomarkers

Publication details

Journal / source
HepatoBiliary Surgery and Nutrition
Volume
15
Issue
3
Pages
93–93
Publication date
11 March 2026
Language
EN