Short- and long-term outcomes after laparoscopic and open liver resection for combined hepatocellular-cholangiocarcinoma patients: a propensity score-matched study
Abstract
Background: The feasibility and safety of laparoscopic liver resection (LLR) and open liver resection (OLR) in combined hepatocellular-cholangiocarcinoma (cHCC-CCA) patients remain controversial. This study compared the clinical outcomes of LLR versus OLR for patients with cHCC-CCA. Methods: Clinicopathological features of cHCC-CCA patients who underwent liver resection (LR) between 2010 and 2022 were retrospectively analyzed. Propensity score matching (PSM) was employed to balance intergroup differences. Univariate and multivariate Cox analyses were employed to identify independent predictors of overall survival (OS). Results: Of the 141 cHCC-CCA patients, 78 underwent LLR and 63 underwent OLR. After PSM, the LLR group had lower estimated blood loss (EBL) (200 vs. 300 mL, P=0.004) and shorter postoperative length of stay (LOS) (10.0 vs. 15.0 days, P
Fields of Study & Subjects
Cholangiocarcinoma and Gallbladder Cancer Studies
Gallbladder and Bile Duct Disorders
Hepatocellular Carcinoma Treatment and Prognosis
Publication details
- Journal / source
- Journal of Gastrointestinal Oncology
- Publisher
- AME Publishing Company
- Volume
- 17
- Issue
- 1
- Pages
- 19–19
- Publication date
- 1 February 2026
- Language
- EN