The effectiveness of high-dose adjunctive corticosteroid therapy in HIV-negative patients with Pneumocystis jirovecii pneumonia
Abstract
Background: pneumonia (PJP) who present with respiratory failure is increasing. However, the optimal dosing regimen remains uncertain. Our study aimed to evaluate the effectiveness of high-dose versus low-dose adjunctive corticosteroid therapy in this population. Methods: This retrospective cohort study included HIV-negative patients diagnosed with PJP who received adjunctive corticosteroid therapy in Zhongnan Hospital of Wuhan University from June 2018 to March 2023. Patients were categorized into high-dose group (≥1 mg/kg/day of prednisone equivalent) and low-dose group (
Fields of Study & Subjects
Pneumocystis jirovecii pneumonia detection and treatment
Pneumonia and Respiratory Infections
Infectious Diseases and Tuberculosis
Publication details
- Journal / source
- Journal of Thoracic Disease
- Publisher
- AME Publishing Company
- Volume
- 18
- Issue
- 1
- Pages
- 16–16
- Publication date
- 1 January 2026
- Language
- EN