A single-center study on prosthesis selection strategy in aortic valve replacement for patients aged 50–65 years

Journal of Thoracic Disease 2026 Open access

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Authors: Jia Sun, Yuqiu He, Xinyi Mao, Xiaofei Han, Junyi Hu, Z Z Zhou, Huang Yuming, Yongfeng Shao, Yefan Jiang
DOI: 10.21037/jtd-2026-1-0490
Cited by: 1

Abstract

Background: The optimal valve type for middle-aged AVR patients remains debated with inconsistent guideline recommendations. To explore valve selection strategy for 50- to 65-year-old undergoing aortic valve replacement (AVR) by comparing long-term outcomes of mechanical vs. biological artificial valves, with age stratification (≤60/>60 years) to guide clinical decisions. Methods: A retrospective cohort study analyzed 341 patients (2009-2016) undergoing valve replacement surgery, categorized into mechanical valve (n=155) and biological valve (n=186) groups. Propensity score matching (PSM) (1:1) was performed in the overall cohort, as well as in the

Fields of Study & Subjects

Cardiac Valve Diseases and Treatments Aortic Disease and Treatment Approaches Congenital Heart Disease Studies

Publication details

Journal / source
Journal of Thoracic Disease
Publisher
AME Publishing Company
Volume
18
Issue
6
Pages
612–612
Publication date
1 June 2026
Language
EN