The role of transrectal doppler ultrasound in the evaluation of rectal lesions: a large-sample analysis of 400+ cases

Background: Color Doppler ultrasonography technology has demonstrated excellent diagnostic performance across diverse clinical scenarios; however, research on its use in rectal tumor evaluation remains underexplored. This study aimed to evaluate the diagnostic value of transrectal ultrasound (TRUS)-derived vascular features in differentiating between malignant and benign rectal lesions, preoperative tumor staging, and monitoring the neoadjuvant therapy (NT) response. Methods: A retrospective cohort of 452 patients with TRUS-detected gastrointestinal lesions was analyzed. Vascular parameters, including peak systolic velocity (PSV), end-diastolic velocity (EDV), and resistive index (RI), were recorded. Histopathological findings served as the diagnostic gold standard. Results: 0.67) (P