Prolonged survival with alectinib in a patient with advanced lung adenocarcinoma: a case report and literature review
Abstract
Background: alterations and additional rare genetic variants, whose clinical relevance is often unclear. Case Description: alteration is currently classified as a variant of uncertain significance, and its functional or clinical impact has not been established. Conclusions: variant. It underscores the long-term efficacy and tolerability of alectinib and highlights the importance of comprehensive genomic profiling in guiding personalized targeted therapy for genetically complex NSCLC.
Fields of Study & Subjects
Lung Cancer Treatments and Mutations
Cancer Genomics and Diagnostics
Lung Cancer Diagnosis and Treatment
Publication details
- Journal / source
- Translational Cancer Research
- Volume
- 15
- Issue
- 1
- Pages
- 70–70
- Publication date
- 1 January 2026
- Language
- EN