Prolonged survival with alectinib in a patient with advanced lung adenocarcinoma: a case report and literature review

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Authors: Man Sun, Dan Zang, Huan Zhou, Jun Chen
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Abstract

Background: alterations and additional rare genetic variants, whose clinical relevance is often unclear. Case Description: alteration is currently classified as a variant of uncertain significance, and its functional or clinical impact has not been established. Conclusions: variant. It underscores the long-term efficacy and tolerability of alectinib and highlights the importance of comprehensive genomic profiling in guiding personalized targeted therapy for genetically complex NSCLC.

Fields of Study & Subjects

Lung Cancer Treatments and Mutations Cancer Genomics and Diagnostics Lung Cancer Diagnosis and Treatment

Publication details

Journal / source
Translational Cancer Research
Volume
15
Issue
1
Pages
70–70
Publication date
1 January 2026
Language
EN