Enhancing future liver remnant hypertrophy: innovative preoperative strategies and emerging technologies

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Authors: Yanxian Ren, Heng Zhou, Krisztian Homicsko, Ping Yue, David Fuks, Wenbo Meng, Emmanuel Melloul
Cited by: 1

Abstract

Tc-mebrofenin hepatobiliary scintigraphy (HBS), four-dimensional (4D)-flow magnetic resonance imaging (MRI), and computed tomography (CT)-based radiomics-enable integrated volumetric-functional assessment and individualized surgical timing. Although PVE remains the benchmark, multimodal, patient-tailored strategies combining hemodynamic, pharmacologic, and cellular interventions, guided by functional imaging, are reshaping the landscape of hepatic surgery. Future randomized trials and translational studies are essential to define optimal algorithms, validate novel therapies, and safely extend curative resection to a broader population of patients with complex liver disease.

Fields of Study & Subjects

Organ Transplantation Techniques and Outcomes Liver physiology and pathology Hepatocellular Carcinoma Treatment and Prognosis

Publication details

Journal / source
Translational Gastroenterology and Hepatology
Publisher
AME Publishing Company
Volume
11
Pages
73–73
Publication date
1 May 2026
Language
EN