Retinopathy of prematurity and cognitive development in enteral docosahexaenoic acid-supplemented preterm infants: a systematic review and meta-analysis

Translational Pediatrics 2026 Open access

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Authors: Ya-Ting Zhang, Cheng-Yu Li, Xiao-Mei Xie, Jun-Yan Wang, Ying Gao, Hui-Shun Ma, Fan Wang
DOI: 10.21037/tp-2026-1-0057
Cited by: 1

Abstract

Background: Docosahexaenoic acid (DHA) plays a pivotal role in brain and retinal maturation. Preterm infants are born DHA-deficient. In this study, we aimed to systematically evaluate the effects of enteral DHA supplementation on retinopathy of prematurity (ROP) and cognitive development in preterm infants. Methods: The PubMed, Embase, Web of Science, Cochrane Library, and ClinicalTrials.gov databases were searched from inception to August 1, 2025. Randomized controlled trials (RCTs) investigating enteral DHA supplementation in preterm infants [

Fields of Study & Subjects

Retinopathy of Prematurity Studies Fatty Acid Research and Health Infant Development and Preterm Care

Publication details

Journal / source
Translational Pediatrics
Publisher
AME Publishing Company
Volume
15
Issue
4
Pages
112–112
Publication date
1 April 2026
Language
EN