Scoliosis in Fibrodysplasia Ossificans Progressiva
Abstract
CASE: Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disorder characterized by progressive heterotopic ossification. Scoliosis may develop and progress rapidly, especially during adolescence. We report 4 patients with FOP and scoliosis during early adolescence: A 12-year-old girl underwent T4-S2 posterior spinal fusion (PSF); another 12-year-old girl underwent T4-S2 PSF; a 13-year-old boy underwent T3-L4 PSF; and a 14-year-old girl was managed nonoperatively because the complex deformity and ankylosed shoulders could not be adequately balanced with surgery. CONCLUSION: In patients with FOP, surgical intervention can reduce thoracic deformity and improve pulmonary function but carries substantial risks, including heterotopic ossification.
Fields of Study & Subjects
Heterotopic Ossification and Related Conditions
Medical Imaging and Pathology Studies
Cervical and Thoracic Myelopathy
Publication details
- Journal / source
- JBJS Case Connector
- Publisher
- Ovid Technologies (Wolters Kluwer Health)
- Volume
- 16
- Issue
- 1
- Publication date
- 1 January 2026
- Language
- EN