Complex Triple Deformity of the Knee Managed with Knee Arthrodesis in a Severe Hemophilia A Patient
Abstract
CASE: An 18-year-old man with severe hemophilia A (without inhibitors) developed severe left knee deformity after an untreated injury, resulting in wheelchair dependence. He underwent knee arthrodesis under factor VIII cover but developed a postoperative hematoma and inhibitor formation. Following evacuation and treatment with activated prothrombin complex concentrate and recombinant factor VII, solid fusion and pain relief were achieved within 6 months. Three years later, he walks independently with improved Lower Extremity Functional Scale and SF-36 scores. CONCLUSION: Knee arthrodesis remains a viable salvage procedure that restores function and quality of life when joint preservation or total knee arthroplasty is unfeasible, especially in resource-limited settings.
Fields of Study & Subjects
Hemophilia Treatment and Research
Bone fractures and treatments
Elbow and Forearm Trauma Treatment
Publication details
- Journal / source
- JBJS Case Connector
- Volume
- 16
- Issue
- 1
- Publication date
- 1 January 2026
- Language
- EN