Sex-specific KDM6A-HNF4A-CREBH network controls lipoprotein cholesterol metabolism and atherosclerosis via epigenetic reprograming of hepatocytes

Research Square 2026 Preprint Open access

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Authors: Rongrong Fan, Lin Chen, Zhanfang Kang, Jennifer Härdfeldt, Ziyi Li, Matteo Pedrelli, Qi Li, Ruining Lyu, Philipp Valina Allo, Xiangru Zheng, Peibin Lin, Jianwen Zeng
+7 more Zhiqiang Huang, Oihane Garcia-Irigoyen, Sviatlana Sukhanava, Paolo Parini, Amélie Bonnefond, Bo Angelin, Eckardt Treuter
DOI: 10.21203/rs.3.rs-6065505/v1
Cited by: 0

Fields of Study & Subjects

Epigenetics and DNA Methylation Cholesterol and Lipid Metabolism Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

Publication details

Journal / source
Research Square
Publication date
5 January 2026
Document type
Preprint