PIK3CA-Mutated Colorectal Cancer Exhibits a Unique Gut Dysbiosis Profile: Insights from a Nationwide Pan-Cancer Screen in Japan

Research Square 2026 Preprint Open access

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Authors: Shogen Boku, Shunsuke A. Sakai, Kentaro Sawada, Satoshi Horasawa, Ayumu Yoshikawa, Yoshiaki Nakamura, Takao Fujisawa, Riu Yamashita, Hironaga Satake, Yoshito Komatsu, Tomohiro Nishina, Manabu Shiozawa
+9 more Takatsugu Ogata, Nobuhisa Matsuhashi, Kentaro Yamazaki, Toshifumi Yamaguchi, Hisateru Yasui, Naoki Takahashi, Shigenori Kadowaki, Tadamichi Denda, Takayuki Yoshino
DOI: 10.21203/rs.3.rs-7874624/v1
Cited by: 0
References: 45

Fields of Study & Subjects

Gut microbiota and health Colorectal Cancer Treatments and Studies Genetic factors in colorectal cancer

Publication details

Journal / source
Research Square
Publication date
12 January 2026
Document type
Preprint