Non-compacted, PET-insensitive amyloid states increase after systemic inflammation and predict neuritic damage across Aβ pathology models and Alzheimer patients

Research Square 2026 Preprint Open access

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Authors: Jonas J. Neher, Ping Liu, Ann‐Christin Wendeln, Jessica Wagner, Fabian Brückner, Jian Sun, Xiaoqin Huang, Thomas Lewis, Lisa Steinbrecher, Nina Sofia Hermann, Xidi Yuan, Yuanyuan Deng
+11 more Angelos Skodras, Natalie Beschörner, Therése Klingstedt, Katleen Wild, Lisa M. Häsler, Marius Lambert, Simon Lindner, Tammaryn Lashley, Matthias Brendel, K. Peter R. Nilsson, Mathias Jucker
DOI: 10.21203/rs.3.rs-8269406/v1
Cited by: 0

Fields of Study & Subjects

Alzheimer's disease research and treatments Neuroinflammation and Neurodegeneration Mechanisms Dementia and Cognitive Impairment Research

Publication details

Journal / source
Research Square
Publication date
13 January 2026
Language
EN
Document type
Preprint