Phenotypic discovery of GABAA receptor-mediated general anesthetics with analgesic activity

Research Square 2026 Preprint Open access

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Authors: Matthew N. McCarroll, Jarret A.P. Weinrich, Alyssa Marinas, Amanda Dombroski, Lain X. Pierce, Xilin Gu, Megan J. Larmore, Jinfeng Teng, Elizabeth Sisko, Christopher R. Andolina, Ricardo Da Luz, Ralph Zhang
+18 more J M Taylor, Douglas Myers-Turnbull, Cole V. M. Helsell, Amanda Carbajal, Madison E. Jewell, Karnika Bhardwaj, Sian Rodriguez-Rosado, Jennifer R. Deuis, Åsa Andersson, Irina Vetter, Bruce P. Bean, Michael P. Bokoch, Brian Shoichet, David Kokel, Ryan E. Hibbs, Allan I. Basbaum, Jason K. Sello, Reid Kinser
DOI: 10.21203/rs.3.rs-8341587/v1
Cited by: 0
References: 67

Fields of Study & Subjects

Anesthesia and Sedative Agents Anesthesia and Neurotoxicity Research Neuroscience and Neuropharmacology Research

Publication details

Journal / source
Research Square
Publication date
13 January 2026
Document type
Preprint