AI-driven structural analysis clarifies novel TNFRSF17 variants of uncertain significance as drivers of resistance to BCMA-targeted immunotherapies in multiple myeloma

Research Square 2026 Preprint Open access

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Authors: Ricardo Kosch, Behnam Yousefi, Nora Constanze Laubach, Marietta S. Truger, Torsten Haferlach, Søren W. Gersting, Raphael Teipel, Piet Sonnemann, Maximilian Al-Bazaz, Jule Cecilia Artzenroth, Lisa Beatrice Leypoldt, Christoph Schaefers
+7 more Maximilian Christopeit, Moritz Kaune, Leo Rasche, Carsten Bokemeyer, Katja Christina Weisel, Stefan Bonn, Winfried H. Alsdorf
DOI: 10.21203/rs.3.rs-8568919/v1
Cited by: 0
References: 41

Fields of Study & Subjects

Multiple Myeloma Research and Treatments CAR-T cell therapy research Monoclonal and Polyclonal Antibodies Research

Publication details

Journal / source
Research Square
Publication date
13 January 2026
Document type
Preprint