Design and Discovery of Phthalazinone-Based Potential PARP Inhibitors: Synthesis, Molecular Docking, ADMET Profiling, and In Vitro Evaluation

Research Square 2026 Preprint Open access

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Authors: Olga V. Mikolaichuk, A. V. Khramchikhin, Mariia A. Skryl’nikova, Dmitrii Antonenko, Aleksei L. Chutko, Tatyana A. Kurgina, Mikhail M. Kutuzov, Kirill V. Timoshchuk, Olga I. Lavrik, Natalia V. Petukhova, М. П. Самойлович, O. Molchanov
+1 more Dmitrii A. Granov
DOI: 10.21203/rs.3.rs-8688192/v1
Cited by: 0

Fields of Study & Subjects

PARP inhibition in cancer therapy Synthesis and biological activity Computational Drug Discovery Methods

Publication details

Journal / source
Research Square
Publication date
4 February 2026
Document type
Preprint