Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma Mimicking Benign Lymphocytic Infiltrates: A Pathologic Masquerade
Abstract
Monomorphic Epitheliotropic Intestinal T-cell Lymphoma (MEITL) is a rare aggressive T-cell lymphoma mostly found in Asia. It accounts for less than 5% of primary gastrointestinal malignant lymphomas, is rapidly progressing, and has a poor prognosis with a median survival of 7 months. The relatively small size of atypical cells coupled with brisk cryptitis can result in a misdiagnosis of lymphocytic proctocolitis. A strong index of suspicion is required to employ an appropriate IHC panel for this diagnosis. In this case report, we want to describe a 50-year-old patient who presented with chronic lower gastrointestinal symptoms and was diagnosed with MEITL involving the large intestine and ileum.
Fields of Study & Subjects
Lymphoma Diagnosis and Treatment
T-cell and Retrovirus Studies
Chronic Lymphocytic Leukemia Research
Publication details
- Journal / source
- Annals of Pathology and Laboratory Medicine
- Volume
- 13
- Issue
- 1
- Pages
- C19–C23
- Publication date
- 5 January 2026
- Language
- EN