Beyond the Matrix: A Rare Case of Pilomatrix Carcinoma with Histologic Insights

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Authors: Nidhi Priya Allie Barla, Prima Shuchita Lakra, Rahul Kumar Bharti, Amiy Arnav, Sanjeet Kumar Singh, Monalisa Katyare
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Abstract

Pilomatrix carcinoma is rare entity which arises from matrical cells of hair follicle and misdiagnosed quite often. A 27 years female with presented with a swelling on right side of nape of neck for approximately 3 years which was painless, slowly progressive, soft to firm in consistency. Previously misdiagnosed as squamous cell carcinoma, the lesion recurred and was excised again in our institution and was diagnosed here as Pilomatrix carcinoma with regional lymph node metastasis. Since she had metastasis, the patient is currently undergoing radiotherapy. Considering the rarity of this carcinoma it was noteworthy to report this case as correct diagnosis aids patient’s treatment protocol and improves prognosis.

Fields of Study & Subjects

Cancer and Skin Lesions Genetic and rare skin diseases. Sympathectomy and Hyperhidrosis Treatments

Publication details

Journal / source
Annals of Pathology and Laboratory Medicine
Volume
13
Issue
1
Pages
C58–C61
Publication date
5 January 2026
Language
EN