Clinical Characteristics and Outcomes of Patients Undergoing Primary PCI for Acute Myocardial Infarction in a Tertiary Care Teaching Institution in North Kerala

Background: Acute myocardial infarction (AMI) remains a leading cause of morbidity and mortality worldwide.Primary percutaneous coronary intervention (PCI) is the gold standard for treatment of ST-segment elevation myocardial infarction (STEMI).This study aims to assess the clinical characteristics, procedural success, and outcomes of patients undergoing primary PCI for AMI in a tertiary care teaching hospital in north Kerala, India.Methods: A retrospective study included 306 patients undergoing primary PCI for acute myocardial infarction at Malabar Medical College Hospital, Kozhikode (July 2023-June 2024).Data on demographics, comorbidities, procedures, and in-hospital outcomes were collected.Primary endpoints were in-hospital mortality, major adverse cardiovascular events (MACE), and procedural complications.Descriptive and inferential statistics were used to analyze associations between clinical characteristics and outcomes.Results: The mean age of participants was 58.5±12.3years, with 65% male and 35% female.Hypertension, diabetes mellitus, and hyperlipidemia were present in 68%, 56%, and 44% of the cohort, respectively.The in-hospital mortality rate was 5%, and the MACE rate was 8%.Diabetes mellitus (OR 3.22, 95% CI 1.21-8.53),multivessel disease (OR 2.56, 95% CI 1.04-6.33),and delayed presentation by more than 6 hours (OR 2.89, 95% CI 1.08-7.70)were identified as independent predictors of adverse outcomes.Conclusion: Primary PCI remains an effective intervention for AMI, with a reasonable in-hospital mortality rate.However, higher comorbidity burden and delayed presentation for primary PCI are significant predictors of poorer outcomes.Timely intervention and optimal management of risk factors are crucial for improving patient outcomes.