Adenomyoepithelioma of the breast: a case report

Background. Adenomyoepithelioma of the breast is a rare benign tumor characterized by biphasic proliferation of epithelial and myoepithelial cells of the lobular and ductal components of the breast. Although benign, adenomyoepithelioma has a potential for malignant transformation; therefore its early detection is crucial. Currently, there are no established clinical, radiological and morphological criteria for early detection of this type of tumor, which can complicate diagnosis and requires histological examination of the tumor. Description of the clinical case. A 39-year-old female patient presented to the Oncology Center No. 1 of the S.S. Yudin Clinical Hospital with the breast neoplasm detected during a routine examination. Ultrasound examination showed fibroadenoma. Histological examination of the trepan biopsy specimen revealed adenomyoepithelioma. The patient underwent a sectoral resection of the right breast. Histology and immunohistochemistry confirmed the diagnosis of adenomyoepithelioma. Conclusion . Breast adenomyoepithelioma is a rare tumor diagnosed by histology/immunohistochemistry, with surgery as a main treatment. Further research is needed to study the pathogenesis.