Pupillary Constriction and Dilatation as a Window into Brainstem and Autonomic Integrity
Abstract
We read with interest the recent letter to the editor addressing patterns of upward, lateral, and downward brain herniation and their correlation with clinical findings in acute intracranial pathologies (1). In that work, the authors discussed relevant neuroanatomical considerations, including the process of intracranial herniation and its relationship to pupillary size and light responsiveness. We wish to elaborate further on pupillary changes, with particular emphasis on variations in size and reactivity and their correlation with the stages of rostrocaudal herniation.
Fields of Study & Subjects
Traumatic Brain Injury and Neurovascular Disturbances
Ophthalmology and Visual Health Research
Takotsubo Cardiomyopathy and Associated Phenomena
Publication details
- Journal / source
- Malaysian Journal of Medical Sciences
- Volume
- 33
- Issue
- 1
- Pages
- 155–165
- Publication date
- 28 February 2026
- Language
- EN