Development of a machine learning model to guide further metastatic biopsy decision in patients with HER2-0 status on both primary breast cancer and first biopsied metastatic site: who should undergo a repeated biopsy to detect HER2-low gain?

SSRN Electronic Journal 2026 Preprint Open access

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Authors: Federica Miglietta, Antonio Collesei, Claudio Vernieri, Tommaso Giarratano, Carlo Alberto Giorgi, Fabio Girardi, Gaia Griguolo, Matilde Cacciatore, Federico Piacentini, Andrea Botticelli, Andrea Vingiani, Lorenzo Casadei
+10 more Giuseppe Fotia, Davide Massa, Pietro Napolitano, Giusy Landa, Dario Palleschi, Giancarlo Pruneri, Rocco Cappellesso, Angelo Paolo Dei Tos, Maria Vittoria Dieci, Valentina Guarneri
DOI: 10.2139/ssrn.6030185
Cited by: 0

Fields of Study & Subjects

HER2/EGFR in Cancer Research Breast Cancer Treatment Studies Gastric Cancer Management and Outcomes

Publication details

Journal / source
SSRN Electronic Journal
Publication date
1 January 2026
Document type
Preprint