Facial Cutaneous Rosai-Dorfman Disease Misdiagnosed as Sporotrichosis: A Case Report and Literature Review
Abstract
Abstract: Cutaneous Rosai-Dorfman disease (CRDD) is a rare form of non-Langerhans cell histiocytosis. Because the etiology and pathogenesis remain unclear and the cutaneous manifestations are highly variable, no definitive diagnostic criteria have been established. As a result, the risk of diagnostic errors and missed diagnoses is common in clinical practice. This report describes the case of a 64-year-old woman with facial CRDD that initially misdiagnosed as sporotrichosis. This case broadens the known clinical spectrum of CRDD and underscores the importance of careful differential diagnosis to avoid misdiagnosis and ensure appropriate treatment. Keywords: Rosai-Dorfman disease, sporotrichosis, histiocytic diseases, sinus histiocytosis with massive lymphadenopathy, emperipolesis
Fields of Study & Subjects
Histiocytic Disorders and Treatments
Cardiac tumors and thrombi
Tuberous Sclerosis Complex Research
Publication details
- Journal / source
- Clinical Cosmetic and Investigational Dermatology
- Publisher
- Informa UK Limited
- Volume
- Volume 19
- Pages
- 1–7
- Publication date
- 1 January 2026
- Language
- EN