Pericoronary Fat Attenuation Index Mediates the Link Between TyG Index and OSA Risk in Type 2 Diabetes

Diabetes Metabolic Syndrome and Obesity 2026 Open access

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Authors: Mei Zhang, Haimei Du, Qin Zhou, Yaxin Yao, Linjuan Li
DOI: 10.2147/dmso.s571891
Cited by: 1
References: 35

Abstract

Objective: The comorbidity of type 2 diabetes mellitus (T2DM) and obstructive sleep apnea (OSA) represents a significant public health challenge. We quantified the mediating role of the coronary fat attenuation index (FAI) in the association between the triglyceride-glucose (TyG) index and OSA risk, characterizing its nonlinear dynamics. Methods: In this retrospective cross-sectional study, we assessed OSA risk using the STOP-Bang questionnaire in 420 patients with T2DM undergoing coronary computed tomography angiography, classifying scores as low-risk (

Fields of Study & Subjects

Cardiovascular Disease and Adiposity Obstructive Sleep Apnea Research Adipokines Inflammation and Metabolic Diseases

Publication details

Journal / source
Diabetes Metabolic Syndrome and Obesity
Publisher
Informa UK Limited
Volume
Volume 19
Pages
1–12
Publication date
1 January 2026
Language
EN