Recent Advances in Glimepiride Solubility Improvement: A Focus on Formulation Technologies – A Narrative Review

International Journal of Nanomedicine 2026 Open access

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Authors: Valentina Fiftianingrum, Iyan Sopyan, Sandra Megantara, Cecep Suhandi
DOI: 10.2147/ijn.s582548
Cited by: 2
References: 97

Abstract

Glimepiride, a second-generation sulfonylurea used in the management of type 2 diabetes mellitus, is classified as a Biopharmaceutics Classification System (BCS) Class II drug. Its severely limited aqueous solubility (

Fields of Study & Subjects

Drug Solubulity and Delivery Systems Advanced Drug Delivery Systems Silymarin and Mushroom Poisoning

Publication details

Journal / source
International Journal of Nanomedicine
Publisher
Informa UK Limited
Volume
Volume 21
Pages
1–15
Publication date
1 January 2026
Language
EN