Cases of Septic Arthritis During Meningitis Infection at Zinder National Hospital, Niger Republic

Abstract: septic arthritis is the consequence of bacterial aggression of the articular synovium, which can occur during meningitis. We report two cases of arthritis in patients hospitalized for meningitis in the infectious and tropical diseases department of Zinder National Hospital. Two cases admitted initially for meningitis at the Zinder National Hospital, developed secondary localized arthritis. Laboratory confirmation was carried out using QIAstat-Dx Meningitis/Encephalitis Panel kit (QIAGEN) on cerebrospinal fluid and joint fluid for the respective diagnosis of meningitis and arthritis. While Haemophilus influenzae and Neisseria meningitis were confirmed in the cerebrospinal fluid, the presence of Haemophilus influenzae and co-infection with Neisseria meningitis and Streptococcus pyogenes was established in the joint fluid. Both patients were cured after antibiotic treatment and symptomatic management. Meningitis can lead to osteoarticular localization in severe forms. Dual antibiotic therapy may improve the prognosis. Keywords: septic arthritis, meningitis, purpura, Zinder, Niger Republic