Adverse Drug Events Associated with Opioid Treatment for Pain After Motor Vehicle Crash

Journal of Pain Research 2026 Open access

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Authors: Andrew Zullo, Steven Balog, Marzan A. Khan, Melissa R. Pfeiffer, Melissa R. Riester, Allison E. Curry, Francesca L. Beaudoin, Arman Oganisian, Brandon D. L. Marshall, Patience M Dow, Beth Dana, Nina R. Joyce
DOI: 10.2147/jpr.s529856
Cited by: 0
References: 32

Abstract

Purpose: Thousands of motor vehicle crash (MVC) related deaths and injuries occur among older adults every year in the United States. Injuries from MVC may cause acute or chronic pain resulting in functional decline and disability. Opioid treatment poses risk of adverse drug events (ADEs) including dependency, overdose, respiratory problems, and other complications. Our objective was to evaluate the comparative risks of ADEs associated with three opioid prescribing strategies: 1) greater versus lesser days' supply (≥6 days versus ≤5 days), 2) higher versus lower doses (≥30 MME versus

Fields of Study & Subjects

Opioid Use Disorder Treatment Pain Management and Opioid Use Pharmaceutical Practices and Patient Outcomes

Publication details

Journal / source
Journal of Pain Research
Volume
Volume 19
Pages
1–14
Publication date
1 January 2026
Language
EN