Sub-tenon’s injection of recombinant prourokinase (Hemase) combined with intravitreal injection of a neoangiogenesis inhibitor (Eylea) in the treatment of massive subretinal hemorrhage in neovascular age-related macular degeneration. A clinical case
Abstract
This paper describes a clinical case of neovascular age-related macular degeneration complicated by subretinal hemorrhage and analyzes the effectiveness of minimally invasive combination treatment, which included a sub-Tenon injection of recombinant prourokinase (Hemase) simultaneously with an intravitreal injection of a neoangiogenesis inhibitor (Eylea). This treatment resulted in significant positive results within a short period of time (1 month), including complete hemorrhage resorption and improved visual acuity, which made it possible to postpone or completely avoid open surgery.
Fields of Study & Subjects
Retinal Diseases and Treatments
Retinal and Macular Surgery
Ocular Diseases and Behçet’s Syndrome
Publication details
- Journal / source
- Russian Ophthalmological Journal
- Volume
- 18
- Issue
- 4
- Pages
- 132–138
- Publication date
- 9 January 2026
- Language
- RU