A clinical case of choroidal melanoma recurrence in the orbit 14 years after enucleation

Uveal melanoma is a multifactorial malignant intraocular tumor of neuroectodermal genesis, developing from melanocytes of the uveal tract, characterized by a high risk of metastasis and a poor vital prognosis. The paper describes the clinical observation of a 67-year-old patient with a late recurrence of choroidal melanoma in orbit in 2024 after enucleation in 2010. Clinically, echographically, and according to computer tomography, the presence of a neoplasm in the orbit has been confirmed. The patient underwent a transconjunctival orbitotomy, and a dark brown pseudocapsule about 2 cm in size was removed. According to the pathohistological conclusion, the morphological picture of the neoplasm of the left orbit corresponded to a recurrence of melanoma with the presence of perineural invasion. The patient is directed to irradiate the left orbit with a narrow medical proton beam. Despite the rarity, such a case demonstrates the need for lifelong monitoring of patients with choroidal melanoma, regardless of the time after surgical treatment, in order to timely identify and treat local and long-term complications.