Effect of Oral Contraceptive Pills on Chronic Pelvic Pain Associated with Endometriosis

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Authors: Mohamed Mohamed Farahat, Abd El-monsef Abdelghaffar Moustafa, Moustafa Algebaly Gado Ismail
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Abstract

Background: Endometriosis is a prevalent etiology of chronic pelvic pain (CPP) in reproductive-age females. Combined oral contraceptive pills (OCPs) are widely utilized as first-line therapy due to their efficacy, safety, and tolerability.Aim: To study the efficacy of oral contraceptive pills on chronic pelvic pain related to endometriosis.Patients and methods: This Prospective randomized clinical trial research has been performed on 60 cases and selected from the outpatient clinic of obstetrics and gynecology at Al-Hussein University Hospital from November 2024 to April 2025.Results: Baseline characteristics were comparable except for parity. The OCP group showed significantly greater reduction in VAS score at 12 weeks (3.73 ± 1.08 vs 5.13 ± 1.10) and 24 weeks (2.5 ± 0.93 vs 5.0 ± 1.28) (p

Fields of Study & Subjects

Endometriosis Research and Treatment Ectopic Pregnancy Diagnosis and Management Menstrual Health and Disorders

Publication details

Journal / source
Al-Azhar International Medical Journal /Al-Azhar International Medical Journal
Volume
0
Issue
0
Pages
238–243
Publication date
27 January 2026
Language
EN