The Efficacy of Left Ventricular Out Flow Tract Velocity Time Integrity, Electrical Cardiometry and Carotid Corrected Flow Time to Predict Fluid Responsiveness in Shocked Patients.
Abstract
Purpose: Electrical cardiometry and echocardiographic measurement of carotid artery corrected flow time (cFT), a heart rate-adjusted measure of systolic flow duration, are non-invasive methods to assess stroke volume (SV) and predict fluid responsiveness. This study aims to evaluate the ability of carotid artery cFT and electrical cardiometry to predict fluid responsiveness in mechanically ventilated shocked patients during the first 24 hours of shock. Materials and Methods: This prospective observational study enrolled 48 patients with early shock (≤24 hours duration) admitted to the Intensive Care Unit (ICU). Hemodynamic parameters (blood pressure, pulse rate), left ventricular outflow tract velocity-time integral (LVOT-VTI), stroke volume variation (SVV), and carotid cFT were measured before and after a passive leg raise (PLR) test. Patients demonstrating a ≥12% increase in LVOT-VTI post-PLR were classified as fluid responders (Group A); others were non-responders (Group B). Results: The mean age was 49.6 ± 14.71 years (Group A) and 55.6 ± 17.8 years (Group B). Both SVV and carotid cFT showed significant changes following PLR: SVV decreased (17.30% to 13.80%) while cFT increased (14.30 ms to 17.10 ms). A statistically significant negative correlation existed between LVOT-VTI and SVV (p
Fields of Study & Subjects
Hemodynamic Monitoring and Therapy
Trauma
Hemostasis
Coagulopathy
Resuscitation
Sepsis Diagnosis and Treatment
Publication details
- Journal / source
- The Egyptian Journal of Intensive care and Emergency Medicine ./The Egyptian Journal of Intensive care and Emergency Medicine
- Volume
- 6
- Issue
- 1
- Pages
- 7–23
- Publication date
- 1 January 2026
- Language
- EN