Urinary Albumin-to-Creatinine Ratio as an Early Marker of Hypertensive Nephropathy.

Background: Hypertension is a major risk factor for renal damage, often manifested by proteinuria and an elevated albumin-to-creatinine ratio (A/C ratio). Early detection of renal involvement is crucial for preventing progression to chronic kidney disease. Objective: To assess the prevalence and severity of proteinuria and A/C ratio in hypertensive patients compared to healthy controls. Methods: This cross-sectional study included 80 subjects: 40 hypertensive patients and 40 healthy controls. All participants underwent clinical evaluation, blood pressure measurement, and laboratory assessment including serum creatinine, urine A/C ratio ,CRP and cardiac function assessed by ECHO Doppler were evaluated for all sublects . Results: Hypertensive patients had significantly higher A/C ratios Mean ± SD (235 ± 320 mg/g) , Median (Range) = 57 (12-1200) compared to controls Mean ± SD (18.3 ± 4.6 mg/g, p