Exploring Food Fortification Potential on Sesame and Wheat Flour for Sensorical and Nutritional Attributes of Doughnuts

Purpose: To assess the thyroid hormone levels (TSH, FT4, and FT3) in healthcare workers exposed to lowdose ionizing radiation and to determine the association between radiation exposure levels and Hypothyroidism in healthcare workers exposed to low-dose ionizing radiation.Methods: The research involved 44 participants aged 20-40 randomly chosen out of the estimated population of 50, as indicated by Krejcie and Morgan's sample size calculation technique.Reflective data of demographics, job classification, and years of service were noted through a questionnaire.Personal dosimeters collected annual radiation dose data, and thyroid function tests (TSH, Free T4, and Free T3) were assessed.Data were analyzed using SPSS to determine statistical significance.Results: Out of 44, the radiology department professionals diagnosed with hypothyroidism were 11.76% and those working in the nuclear medicine department were 40.74% (p=0.04).And 53% with 16 or more years of exposure were affected (p=0.027).The relationship between the level of radiation exposure and the occurrence of hypothyroidism is very much established.Among the individuals diagnosed with hypothyroidism, 58.82% were within a higher range than the normal range of radiation exposure, and only 11.11% were within the normal range of radiation exposure.On the contrary, in the control group, that is, among persons who did not have hypothyroidism, 88.89% were at normal levels of radiation exposure, whereas it was in excess 41.18% with a significant p value (0.001) Conclusion: Long-term radiation exposure exceeding a standard level is correlated with serious changes in thyroid functionality, involving hypothyroidism.Besides, abnormal TSH, Free T4, and Free T3 levels were seen in those participants with increased radiation levels, and significantly diagnosed with hypothyroidism, which evidences the connection between work-related radiation and thyroid dysfunction.