Fatal Fungal Peritonitis Caused by Aspergillus udagawae: An Autopsy Case Report

Internal Medicine 2026 Open access

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Authors: Kengo Nishino, Takumi Kiwamoto, Chio Sakai, Natsumi Kawamatsu, Takahiro Takeishi, Kenya Kuramoto, Kazufumi Yoshida, Yusuke Ohara, Chikako Tsurushige, Katsuhiko Kamei, Nobuyuki Hizawa
DOI: 10.2169/internalmedicine.6744-25
Cited by: 0
References: 24

Abstract

A 56-year-old man with chronic progressive pulmonary aspergillosis due to multidrug-resistant Aspergillus udagawae presented with acute abdominal pain. Computed tomography revealed rupture of an intra-abdominal abscess with ascites. Despite emergency surgery for peritonitis, he died on day 5. Autopsy showed numerous fungal abscesses with direct invasion and hematogenous spread from the lungs to the peritoneum. A genetic analysis confirmed A. udagawae. This represents the first autopsy-proven case of fatal fungal peritonitis secondary to invasive pulmonary aspergillosis caused by A. udagawae, highlighting the importance of molecular identification in treatment-refractory Aspergillus infections.

Fields of Study & Subjects

Antifungal resistance and susceptibility Fungal Infections and Studies Plant Pathogens and Fungal Diseases

Publication details

Journal / source
Internal Medicine
Volume
65
Issue
18
Pages
2525–2530
Publication date
9 February 2026
Language
EN