Endoscopic Submucosal Dissection as a Diagnostic and Minimally Invasive Therapeutic Excision Modality for Primary Anorectal Malignant Melanoma
Abstract
Primary anorectal malignant melanoma is a rare mucosal malignancy with nonspecific symptoms, frequent misdiagnoses, delayed treatment, and the lack of an established standard therapeutic strategy are the reasons for a poor prognosis. Diagnostic challenges are further compounded by the low rate of preoperative histological confirmation, especially for amelanotic lesions. Given its poor prognosis, performing a less invasive resection is crucial. We herein report the case of an 82-year-old male patient who underwent endoscopic submucosal dissection as a total biopsy and was treated with immune checkpoint inhibitors as adjuvant therapy.
Fields of Study & Subjects
Cutaneous Melanoma Detection and Management
Colorectal and Anal Carcinomas
Colorectal Cancer Surgical Treatments
Publication details
- Journal / source
- Internal Medicine
- Volume
- 65
- Issue
- 20
- Pages
- 2690–2694
- Publication date
- 9 February 2026
- Language
- EN