Conventional Therapies and Challenges in the Treatment of Psoriasis

Psoriasis is an autoimmune disease that re-emerges through the proliferation of keratinocytes. It occurs at any age, but is usually observed in temperate regions. It has a global population of 2 to 5 percent on average. The treatment of psoriasis remains a daunting task, with various challenges affecting treatment, including patient compliance and adherence, delicate patient profiles, psychological aspects, and skin as an obstacle to current delivery. Psoriasis is characterized by an excessive proliferation of cells, resulting in painful skin spots due to the absence of normal skin cell replacement, which occurs every 3 to 4 weeks. Treatment strategies for psoriasis depend on the severity and location of the injuries. The current chapter reviews the therapies and challenges associated with current treatments, including topical therapy, oral therapy, biological therapy, parenteral therapy, and phototherapy.